Suggested Empiric Antimicrobial Agents of Choice (7th Edition) Wausau Hospital 2006-2008 Infectious Disease Section & Pharmacy and Therapeutics Committee ©WAB/2006

V. PYLEONEPHRITIS, OR SEPSIS Due to UTI.
• Community-Acquired/Normal Host: Cipro 200mg IV q 12h (or 500mg PO q 12h) or Ceftriaxone 1gm q 24h, PLUS Ampicillin 2gm q 6h; + Tobramycin (ODA x 1-2 days).
• Health Care-Associated: Cefepime 2gm q 12h PLUS, Cipro 200mg IV q 12h (or, 500mg PO q 12h), PLUS Ampicillin 2gm q 6h; + Tobramycin (ODA x 1-2 days)
• Streamlining and Switch (PO) Therapy: change to narrower-spectrum agent(s) based on microbiology results: Bactrim DS BID or Cipro 500mg BID or Amoxicillin 500mg TID.